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There are several matches for 'glutamate carboxypeptidase'.
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2090 matches
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organism
protein
1)
Homo sapiens
FOLH1 -
Glutamate
carboxypeptidase
2; Has both folate hydrolase and N-acetylated-alpha-linked- acidic dipeptidase (NAALADase) activity. Has a preference for tri- alpha-
glutamate
peptides. In the intestine, required for the uptake of folate. In the brain, modulates excitatory neurotransmission through the hydrolysis of the neuropeptide, N-aceylaspartylglutamate (NAAG), thereby releasing
glutamate
. Involved in prostate tumor progression.
[a.k.a. 2JBK, 4OC1, PSM]
2)
Homo sapiens
AGBL5 - Cytosolic
carboxypeptidase
-like protein 5; Metallocarboxypeptidase that mediates protein deglutamylation. Specifically catalyzes the deglutamylation of the branching point
glutamate
side chains generated by post-translational glutamylation in proteins such as tubulins. In contrast, it is not able to act as a long-chain deglutamylase that shortens long polyglutamate chains, a process catalyzed by AGTPBP1/CCP1, AGBL2/CCP2, AGBL3/CCP3, AGBL1/CCP4 and AGBL4/CCP6. Mediates deglutamylation of CGAS, regulating the antiviral activity of CGAS.
[a.k.a. ENSP00000323681, AC013472, XM_011533012.2]
3)
Homo sapiens
AGTPBP1 - Cytosolic
carboxypeptidase
1; Metallocarboxypeptidase that mediates deglutamylation of target proteins. Catalyzes the deglutamylation of polyglutamate side chains generated by post-translational polyglutamylation in proteins such as tubulins. Also removes gene-encoded polyglutamates from the carboxy-terminus of target proteins such as MYLK. Acts as a long-chain deglutamylase and specifically shortens long polyglutamate chains, while it is not able to remove the branching point
glutamate
, a process catalyzed by AGBL5/CCP5.
[a.k.a. NP_001317630.1, M14.028, XM_017014548.2]
4)
Homo sapiens
AGBL1 - Cytosolic
carboxypeptidase
4; Metallocarboxypeptidase that mediates deglutamylation of target proteins. Catalyzes the deglutamylation of polyglutamate side chains generated by post-translational polyglutamylation in proteins such as tubulins. Also removes gene-encoded polyglutamates from the carboxy-terminus of target proteins such as MYLK. Acts as a long-chain deglutamylase and specifically shortens long polyglutamate chains, while it is not able to remove the branching point
glutamate
, a process catalyzed by AGBL5/CCP5.
[a.k.a. Cytosolic carboxypeptidase protein 4, Q96MI9, AC016180]
5)
Homo sapiens
AGBL4 - Cytosolic
carboxypeptidase
6; Metallocarboxypeptidase that mediates deglutamylation of target proteins. Catalyzes the deglutamylation of polyglutamate side chains generated by post-translational polyglutamylation in proteins such as tubulins. Also removes polyglutamates from the carboxy-terminus of target proteins such as MYLK. Mediates deglutamylation of CGAS, regulating the antiviral activity of CGAS. Acts as a long-chain deglutamylase and specifically shortens long polyglutamate chains, while it is not able to remove the branching point
glutamate
, a process catalyzed by AGBL5/CCP5.
[a.k.a. ENST00000334103, AK027348, NM_032785.3]
6)
Mus musculus
Folh1 -
Glutamate
carboxypeptidase
2; Has both folate hydrolase and N-acetylated-alpha-linked- acidic dipeptidase (NAALADase) activity. Has a preference for tri- alpha-
glutamate
peptides (By similarity). In the intestine, required for the uptake of folate. In the brain, modulates excitatory neurotransmission through the hydrolysis of the neuropeptide, N- aceylaspartylglutamate (NAAG), thereby releasing
glutamate
.
[a.k.a. 53320, Q0VDM5, R-MMU-8963693]
7)
Mus musculus
Agbl5 - Cytosolic
carboxypeptidase
-like protein 5; Metallocarboxypeptidase that mediates protein deglutamylation. Specifically catalyzes the deglutamylation of the branching point
glutamate
side chains generated by post-translational glutamylation in proteins such as tubulins. In contrast, it is not able to act as a long-chain deglutamylase that shortens long polyglutamate chains, a process catalyzed by AGTPBP1/CCP1, AGBL2/CCP2, AGBL3/CCP3, AGBL1/CCP4 and AGBL4/CCP6. Mediates deglutamylation of CGAS, regulating the antiviral activity of CGAS.
[a.k.a. XM_006503870.1, CCDS80242.1, XM_006503877]
8)
Mus musculus
Agtpbp1 - Cytosolic
carboxypeptidase
1; Metallocarboxypeptidase that mediates deglutamylation of target proteins. Catalyzes the deglutamylation of polyglutamate side chains generated by post-translational polyglutamylation in proteins such as tubulins. Also removes gene-encoded polyglutamates from the carboxy-terminus of target proteins such as MYLK. Acts as a long-chain deglutamylase and specifically shortens long polyglutamate chains, while it is not able to remove the branching point
glutamate
, a process catalyzed by AGBL5/CCP5. Deglutamylation plays a key role in cerebellar Purkinje cell dif [...]
[a.k.a. ENSMUSP00000132854, AK013688, AAH82335.1]
9)
Mus musculus
Agbl1 - Cytosolic
carboxypeptidase
4; Metallocarboxypeptidase that mediates deglutamylation of target proteins. Catalyzes the deglutamylation of polyglutamate side chains generated by post-translational polyglutamylation in proteins such as tubulins. Also removes gene-encoded polyglutamates from the carboxy-terminus of target proteins such as MYLK. Acts as a long-chain deglutamylase and specifically shortens long polyglutamate chains, while it is not able to remove the branching point
glutamate
, a process catalyzed by AGBL5/CCP5.
[a.k.a. Cytosolic carboxypeptidase protein 4, EG244071, NM_001199224]
10)
Mus musculus
Agbl4 - Cytosolic
carboxypeptidase
6; Metallocarboxypeptidase that mediates deglutamylation of target proteins. Catalyzes the deglutamylation of polyglutamate side chains generated by post-translational polyglutamylation in proteins such as tubulins. Also removes polyglutamates from the carboxy-terminus of target proteins such as MYLK. Mediates deglutamylation of CGAS, regulating the antiviral activity of CGAS. Acts as a long-chain deglutamylase and specifically shortens long polyglutamate chains, while it is not able to remove the branching point
glutamate
, a process catalyzed by AGBL5/CCP5.
[a.k.a. XP_011238955.1, XP_011238955, ABI51958.1]
11)
Caenorhabditis elegans
gcp-2.3 -
Glutamate
CarboxyPeptidase
2 homolog.
[a.k.a. C35C5.11.1, Q58A98, NP_001024446.1]
12)
Caenorhabditis elegans
gcp-2.2 -
Glutamate
CarboxyPeptidase
2 homolog.
[a.k.a. C35C5.2, 183230, WBGene00007954]
13)
Caenorhabditis elegans
gcp-2.1 -
Glutamate
carboxypeptidase
2 homolog; Belongs to the peptidase M28 family. M28B subfamily.
[a.k.a. R57.1a, 3.4.17.21, Q65ZG4]
14)
Caenorhabditis elegans
ccpp-6 - Cytosolic
carboxypeptidase
6; Metallocarboxypeptidase that catalyzes the removing of polyglutamate side chains that are present on the gamma-carboxyl group of
glutamate
residues of tubulin in sensory cilia. Probably via the deglutamylation of tubulin, promotes microtubule stability required for axon regrowth after injury. Also regulates microtubule dynamics in uterine muscle cells. Belongs to the peptidase M14 family.
[a.k.a. EEED8.6, WBGene00017136, 184043]
15)
Acetonema longum
ALO_04588 -
Glutamate
carboxypeptidase
; COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases.
[a.k.a. EGO65097.1, F7NFT6_9FIRM, 3.4.17.11,
Glutamate carboxypeptidase
,
glutamate carboxypeptidase
, ...]
16)
Achromobacter arsenitoxydans
KYC_06991 -
Glutamate
carboxypeptidase
; COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases.
[a.k.a. EHK67099.1, NZ_AGUF01000031.1, H0F3P4_9BURK,
Glutamate carboxypeptidase
,
glutamate carboxypeptidase
, ...]
17)
Achromobacter denitrificans
OLU07025.1 - Peptidase; Derived by automated computational analysis using gene prediction method: Protein Homology.
[a.k.a. BVK87_17240, A0A427WSI0,
Glutamate carboxypeptidase
]
18)
Achromobacter denitrificans
OLU02871.1 - Catalyzes the release of C-terminal glutamate residues from N-acylating moieties; Derived by automated computational analysis using gene prediction method: Protein Homology.
[a.k.a. BVK87_25520, OLU02871, M20/M25/M40 family metallo-hydrolase,
Glutamate carboxypeptidase
,
glutamate carboxypeptidase
, ...]
19)
Achromobacter insolitus
cpg2_2 - Catalyzes the release of C-terminal glutamate residues from N-acylating moieties; Derived by automated computational analysis using gene prediction method: Protein Homology.
[a.k.a. APX74646.1, BUW96_06980,
Glutamate carboxypeptidase
,
glutamate carboxypeptidase
]
20)
Achromobacter insolitus
cpg2_1 - Peptidase; Derived by automated computational analysis using gene prediction method: Protein Homology.
[a.k.a. APX79050.1, BUW96_27720,
Glutamate carboxypeptidase
]
2090 matches
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